2 resultados para medication quality and safety

em Indian Institute of Science - Bangalore - Índia


Relevância:

100.00% 100.00%

Publicador:

Resumo:

Seasonal studies were carried out from 21 stations, comprising of three zones, of Cochin Estuary, to assess the organic matter quality and trophic status. The hydographical parameters showed significant seasonal variations and nutrients and chlorophylls were generally higher during the monsoon season. However, chemical contamination along with the seasonal limitations of light and nitrogen imposed restrictions on the primary production and as a result, mesotrophic conditions generally prevailed in the water column. The nutrient stoichometries and delta C-13 values of surficial sediments indicated significant allochthonous contribution of organic matter. Irrespective of the higher content of total organic matter, the labile organic matter was very low. Dominance of carbohydrates over lipids and proteins indicated the lower nutritive aspect of the organic matter, and their aged and refractory nature. This, along with higher amount of phytodetritus and the low algal contribution to the biopolymeric carbon corroborated the dominance of allochthonous organic matter and the heterotrophic nature. The spatial and seasonal variations of labile organic components could effectively substantiate the observed shift in the productivity pattern. An alternative ratio, lipids to tannins and lignins, was proposed to ascertain the relative contribution of allochthonous organic matter in the estuary. This study confirmed the efficiency of an integrated biogeochemical approach to establish zones with distinct benthic trophic status associated with different degrees of natural and anthropogenic input. Nevertheless, our results also suggest that the biochemical composition alone could lead to erroneous conclusions in the case of regions that receive enormous amounts of anthropogenic inputs.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

One of the challenges for accurately estimating Worst Case Execu-tion Time(WCET) of executables is to accurately predict their cache behaviour. Various techniques have been developed to predict the cache contents at different program points to estimate the execution time of memory-accessing instructions. One of the most widely used techniques is Abstract Interpretation based Must Analysis, which de-termines the cache blocks guaranteed to be present in the cache, and hence provides safe estimation of cache hits and misses. However,Must Analysis is highly imprecise, and platforms using Must Analysis have been known to produce blown-up WCET estimates. In our work, we propose to use May Analysis to assist the Must Analysis cache up-date and make it more precise. We prove the safety of our approach as well as provide examples where our Improved Must Analysis provides better precision. Further, we also detect a serious flaw in the original Persistence Analysis, and use Must and May Analysis to assist the Persistence Analysis cache update, to make it safe and more precise than the known solutions to the problem.